Corbus Pharmaceuticals Reports Promising Results for SYS6002 in Nectin-4 Positive Tumor Treatment

Emerging as a significant player in the realm of targeted cancer therapies, Corbus Pharmaceuticals Holdings, Inc. CRBP has revealed noteworthy clinical progression concerning their advanced antibody drug conjugate, SYS6002 (CRB-701). Focused on Nectin-4 positive tumors, the company's treatment continues to exhibit a favorable safety profile and encouraging efficacy results. An update was recently presented at the renowned American Society of Clinical Oncology (ASCO) 2024 meeting.

Clinical Study Expansion and Efficacy Results

Since January 2024, the clinical study for SYS6002 has witnessed a substantial increase with 19 additional patients enrolled, augmenting the total participation to 37. Out of these, 25 have been evaluated for the drug's effectiveness. Statistics are positively indicating a 44% Objective Response Rate (ORR) and 78% Disease Control Rate (DCR) in patients with metastatic urothelial cancer (mUC), while the rates stand at 43% ORR and 86% DCR for cervical cancer - these results pertain to administered doses of 1.2mg/Kg or higher.

Company Background and Research Focus

CRBP Corbus Pharmaceuticals Holdings, Inc., situated in Norwood, Massachusetts, operates primarily as a clinical-stage pharmaceutical establishment with a keen focus on pioneering therapies. The company’s research targets the endocannabinoid system across different medical spectrums such as autoimmunity, fibrosis, and notably, cancer. SYS6002 represents a critical component of Corbus's innovative drug pipeline, as it aligns with their mission to advance treatment options in oncology.

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